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논문 기본정보
Genotoxicity of low-dose Glyphosate by Sister Chromatid Exchange
논문 개요
| 기관명 | NDSL |
|---|---|
| 저널명 | 대한임상독성학회지 = Journal of the Korean Society of Clinical Toxicology |
| ISSN | 1738-1320, |
| ISBN |
논문저자 및 소속기관 정보
| 저자(한글) | Lee, Sang Hoon,Kim, Sung Jin,Choi, Woo Ik,Jin, Sang Chan,Choi, In Jang,Lee, Jae Ho |
|---|---|
| 저자(영문) | |
| 소속기관 | |
| 소속기관(영문) | |
| 출판인 | |
| 간행물 번호 | |
| 발행연도 | 2014-01-01 |
| 초록 | Purpose: Glyphosate (N-phosphonomethyl glycine) is widely used as an herbicide for weed control in rural areas. It is also readily available for suicide attempts. Glyphosate has high toxicity and negatively affects the human body. The aim of this investigation was to study the genotoxicity of a low-concentration of glyphosate through sister chromatid exchange (SCE) in human blood lymphocytes in vitro. Methods: Primary lymphocyte cultures were obtained from blood samples of 11 males and seven females who had been exposed to glyphosate (0, 100, 200, and 300 ng/mL). The frequency of SCEs was examined and statistical analysis was performed. Results: All doses of glyphosate induced a significant dose-dependent increase in SCE frequency compared with the control group (P |
| 원문URL | http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=03553784&target=NART&cn=JAKO201429638663627 |
| 첨부파일 |
추가정보
| 과학기술표준분류 | |
|---|---|
| ICT 기술분류 | |
| DDC 분류 | |
| 주제어 (키워드) | Glyphosate,Toxicology,Sister chromatid exchange |