| 초록 |
The purpose of this study is to investigate effects of White Ginseng-Ejung-tang (EG) and Red Ginseng-Ejung-tang (ER) water extract on production of various cytokines such as interleukin (IL)-21, IL-25, IL- $28{ beta}$ , erythropoietin (EPO), Exodus-2, monocyte chemotactic protein (MCP)-5, macrophage inflammatory protein (MIP)- $3{ alpha}$ , MIP- $3{ beta}$ , Fractalkine, and TARC in RAW 264.7 mouse macrophages stimulated by lipopolysaccharide (LPS). Levels of cytokines were measured by High-throughput multiplex bead array cytokine assay based on xMAP (multi-analyte profiling beads) technology. ER significantly decreased levels of IL-21, IL-25, IL- $28{ beta}$ , EPO, Exodus-2, MCP-5, MIP- $3{ alpha}$ , MIP- $3{ beta}$ , TARC, and fractalkine for 24 h incubation at the oncentrations of 25 and 100 ${ mu}g/mL$ in LPS-induced RAW 264.7 (P $28{ beta}$ , and chemokines such as EPO, MCP-5, MIP- $3{ alpha}$ , MIP- $3{ beta}$ , Fractalkine, Exodus-2, and TARC in LPS-induced macrophages. |
