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논문 기본정보
Relationship Between Immediate β-Laetam Allergy and Polymorphism of Interleukin-10 Gene
논문 개요
| 기관명 | NDSL |
|---|---|
| 저널명 | 中華醫院感染學雜志 = Chinese journal of nosocomiology |
| ISSN | 1005-4529, |
| ISBN |
논문저자 및 소속기관 정보
| 저자(한글) | LIU, Xinyue,WEI, Wansheng,LI, Chunfeng,LU, Minghua,YANG, Lan |
|---|---|
| 저자(영문) | |
| 소속기관 | |
| 소속기관(영문) | |
| 출판인 | |
| 간행물 번호 | |
| 발행연도 | 2008-01-01 |
| 초록 | OBJECTIVE To investigate the association between 592C/A and-819C/T of interleukin-10 gene polymorphism in patients with immediate β-lactam drug allergy in Chinese Han population.METHODS The genotype and allele frequency of interleukin-10 gene were studied by polymerase chain reaction-restriction fragment length polymorphism(PCR-RFLP)in 44 Chinese Han patients with evidence of immediate β-lactam drug allergy and 44 controls subjects.They all matched for sex and atopy,the production was investigated by sequence analysis.RESULTS Our analysis did reveal differences in the distribution of the single nucleotide polymorphism(SNP)between female allergic patients and controls.Among allergy subjects,we found two distinct significant associations between immediate drug allergy women and two linked IL-10 promoter genes polymorphism,-592C/A and-819C/T(P |
| 원문URL | http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=03553784&target=NART&cn=NART51531176 |
| 첨부파일 |
추가정보
| 과학기술표준분류 | |
|---|---|
| ICT 기술분류 | |
| DDC 분류 | |
| 주제어 (키워드) | β-Lactam allergy,Interleukin-10,Single nucleotide polymorphism |