초록 |
Objective To investigate the histogenesis, clinicopathological features of adult mesoblastic nephroma (MN) and its differential diagnosis. Methods A case of adult MN was studied by light microscopy and immunohistochemistry. The morphological features and the relevant literatures were reviewed. Results The tumor was composed of epithelial and mesenchymal cells. The mesenchymal cells were spindle fibroblasts which displayed smooth muscle cell or myofibroblastic differentiation, and oval nuclei and small nucleoli were observed. The isolated tubules or cysts were seen at the periphery and center of the tumor. Immunohistochemically, the stromal cells were positive for Vim and SMA, but negative for CK and EMA. Conclusion The adult MN is a rare benign composite renal tumor that can be differentiated from other malignant renal tumor by immunohistochemistry and treated successfully by complete excision. |