| 저자(한글) |
Mok, F.P.S.,Samartzis, D.,Karppinen, J.,Fong, D.Y.T.,Luk, K.D.K.,Cheung, K.M.C. |
| 초록 |
Background Context: Modic changes (MC) are bone marrow lesions on magnetic resonance imaging (MRI), suggestive of being associated with low back pain (LBP). Data on determinants of MC and their association with disc degeneration and other spinal phenotypes, as well as that of LBP, rely mostly on small-scale patient populations and remain controversial. Purpose: This study addressed the potential determinants of MC and their association with disc degeneration and LBP among Southern Chinese. Study Design/Setting: A cross-sectional, population-based study was carried out. Patient Sample: This study consisted of 2,449 Southern Chinese volunteers. Methods: Sagittal T2-weighted MRIs of the lumbar spine were assessed for the presence of MC and other spinal phenotypes (eg, disc degeneration, disc displacement, Schmorl nodes) in all individuals. Subjects' demographics, occupation, lifestyle, and clinical profiles were assessed. Results: The overall prevalence of MC was 5.8% (n=141), which increased with advancing age. Modic changes predominantly occurred at the lowest two lumbar levels (83%). In the multivariate analyses, only the presence of disc displacement and a higher disc degeneration score were associated with MC at the upper lumbar levels (L1/L2-L3/L4) (p |
