Detection of Quinolone Resistance Gene in Enterobacter cloacae
기관명 | NDSL |
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저널명 | 中華醫院感染學雜志 = Chinese journal of nosocomiology |
ISSN | 1005-4529, |
ISBN |
저자(한글) | LI, Yan,XU, Shuzhen,SU, Jianrong,LIU, Zhiyuan |
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저자(영문) | |
소속기관 | |
소속기관(영문) | |
출판인 | |
간행물 번호 | |
발행연도 | 2008-01-01 |
초록 | OBJECTIVE To investigate the appearance of quinolone resistance gene(qnr)in Enterobacter cloacae for clinical treatment.METHODS E.cloacae was identified by VITEK-AMS;detection of qnr and extended-spectrum β-lactamases(ESBLs)resistant genes were performed by PCR.Plasmid conjugation test was used to determine the transmission of qnr.The antibotic susceptibility of E.cloacae was detected according to the CLSI guideline.RESULTS The incident rate of E.cloacae with qnr was 23.6% in 55 strains.The sensitive rate to ciprofloxacin was 46.2% in isolates with qnr,but it was 83.3% in isolates without qnr.qnr Genes of 38.2% ESBLs isolates were positive.Two strains harboring qnr genes were conjugated successfully.CONCLUSIONS ESBLs strains usually harbor qnr genes.qnr Genes can be horizontally transferred to recipient by plasmid conjugated test. |
원문URL | http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=03553784&target=NART&cn=NART51531029 |
첨부파일 |
과학기술표준분류 | |
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ICT 기술분류 | |
DDC 분류 | |
주제어 (키워드) | Quinolone resistance gene,Enterobacter cloacae,β-Lactamases,Drug resistance |