Effect of 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol on Immune Functions in Healthy Adults in a Randomized Controlled Trial
기관명 | NDSL |
---|---|
저널명 | Immune network : official journal of the Korean association of immunobiologists |
ISSN | 1598-2629,2092-6685 |
ISBN |
저자(한글) | Hwang, Hee-Jin,Sohn, Ki-Young,Han, Yong-Hae,Chong, Saeho,Yoon, Sun Young,Kim, Young-Jun,Jeong, Jinseoun,Kim, Sang-Hwan,Kim, Jae Wha |
---|---|
저자(영문) | |
소속기관 | |
소속기관(영문) | |
출판인 | |
간행물 번호 | |
발행연도 | 2015-01-01 |
초록 | We previously reported that 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (PLAG) accelerates hematopoiesis and has an improving effect on animal disease models such as sepsis and asthma. The effects of PLAG supplementation on immune modulation were assessed in healthy men and women. The objective was to evaluate the effects of PLAG supplementation on immune regulatory functions such as activities of immune cells and cytokine production. A randomized double blind placebo-controlled trial was conducted. Seventy-five participants were assigned to one of two groups; all participants had an appropriate number of white blood cells on the testing day. The PLAG group (n=27) received oral PLAG supplements and the control group (n=22) received oral soybean oil supplements. IL-4 and IL-6 production by peripheral blood mononuclear cells (PBMC) were lower (p $ gamma$ by PBMC was unaltered with PLAG supplementation. The B cell proliferation decreased significantly in the PLAG group compared to the soybean oil control (p |
원문URL | http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=03553784&target=NART&cn=JAKO201521059282584 |
첨부파일 |
과학기술표준분류 | |
---|---|
ICT 기술분류 | |
DDC 분류 | |
주제어 (키워드) | Human,Lipid supplement,Nutrition,Immunomodulation,PLAG (1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol) |