Can MRI biomarkers at 3 T identify low-risk ductal carcinoma in situ?
기관명 | NDSL |
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저널명 | Clinical imaging |
ISSN | 0899-7071,1873-4499 |
ISBN |
저자(한글) | Rahbar, H.,Parsian, S.,Lam, D.L.,Dontchos, B.N.,Andeen, N.K.,Rendi, M.H.,Lehman, C.D.,Partridge, S.C. |
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저자(영문) | |
소속기관 | |
소속기관(영문) | |
출판인 | |
간행물 번호 | |
발행연도 | 2016-01-01 |
초록 | Objective: The objective was to explore whether 3-T magnetic resonance imaging (MRI) can identify low-risk ductal carcinoma in situ (DCIS). Methods: Dynamic contrast-enhanced and diffusion-weighted (DWI) MRI features of 36 DCIS lesions [8 low risk, Van Nuys Pathologic Classification (VNPC) 1; 28 high risk, VNPC 2/3] were reviewed. An MRI model that best identified low-risk DCIS was determined using multivariate logistic regression. Results: Low-risk DCIS exhibited different DWI properties [i.e., higher contrast-to-noise ratio (P=.02) and lower normalized apparent diffusion coefficients (P=.04)] than high-risk DCIS. A model combining these DWI features provided best performance (area under receiver operating characteristic curve =0.86). Conclusions: DWI may help identify DCIS lesions requiring less therapy. |
원문URL | http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=03553784&target=NART&cn=NART74632434 |
첨부파일 |
과학기술표준분류 | |
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ICT 기술분류 | |
DDC 분류 | |
주제어 (키워드) | Ductal carcinoma in situ,MRI,Biomarker,Diffusion-weighted imaging |