가토에서의 Praziquantel의 체내 동태
기관명 | NDSL |
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저널명 | 약학회지 = Yakhak hoeji |
ISSN | 0377-9556,2383-9457 |
ISBN |
저자(한글) | 이미정,심창구,이민화,김신근,서울대학교 약학대학,서울대학교 약학대학,서울대학교 약학대학,서울대학교 약학대학 |
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저자(영문) | |
소속기관 | |
소속기관(영문) | |
출판인 | |
간행물 번호 | |
발행연도 | 1990-01-01 |
초록 | Pharmacokinetic studies on praziquantel in rabbits were performed in this paper. The pharmacologically active parent drug was separated from the pharmacologically inactive metabolites by HPLC method. The pharmacokinetic parameters of parent drug were obtained. In vitro partition to blood cells of praziquantel was measured. The mean value (n = 3) of partition to blood cells was 44% at concentrations between $1 ;{ mu}g/ml$ and $40 ;{ mu}g/ml$. Therefore, the relatively high partition to blood cells should be considered in further pharmacokinetic studies on praziquantel. |
원문URL | http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=03553784&target=NART&cn=JAKO199003038865389 |
첨부파일 |
과학기술표준분류 | |
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ICT 기술분류 | |
DDC 분류 | |
주제어 (키워드) | Praziquantel,Pharmacokinetics |