| 저자(한글) |
RUAN, Wei,YANG, Zuosheng,WU, Yimou,REN, Lin,TANG, Manjuan |
| 초록 |
OBJECTIVE To study the expression situation of esp gene and the relativity between esp gene and resistance of Enterococcus faecalis derived-infection. METHODS The E. faecalis esp gene was amplified by PCR, then it was cloned and sequenced; the minimum inhibitory concentration (M/C) of five antimicrobicals against E. faecalis was determined by agar dilution method. RESULTS The positive rate of esp gene in 61 strains of E. faecalls was 42.6%the positive rate of esp gene in the resistant strains against ampicillin, ciprofloxacin, high-level gentamicin, and erythromycin was 33.3%, 54.8%, 70.6%, and 51.0%, respectively, and the positive rate of esp gene in the susceptible strains against above 4 antibacterials was 43. 6%, 30. 0%, 7. 4%, and 8. 3%, respectively. CONCLUSIONS Incidence of esp gene does not correlate with the resistance of E. faecalis against ampicillin, but clearly correlate with the resistance of E. faecalis against ciprofloxacin, high-level gentamicin, and erythromycin; esp could become a marker of high-level gentamicin against E. faecalis derived-infection. |
