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논문 기본정보
Altered resting-state functional connectivity in late-life depression: A cross-sectional study
논문 개요
| 기관명 | NDSL |
|---|---|
| 저널명 | Journal of affective disorders |
| ISSN | 0165-0327,1573-2517 |
| ISBN |
논문저자 및 소속기관 정보
| 저자(한글) | Eyre, H.A.,Yang, H.,Leaver, A.M.,Van Dyk, K.,Siddarth, P.,Cyr, N.St.,Narr, K.,Ercoli, L.,Baune, B.T.,Lavretsky, H. |
|---|---|
| 저자(영문) | |
| 소속기관 | |
| 소속기관(영문) | |
| 출판인 | |
| 간행물 번호 | |
| 발행연도 | 2016-01-01 |
| 초록 | Background: Disrupted brain connectivity is implicated in the pathophysiology of late-life depression (LLD). There are few studies in this area using resting-state functional magnetic resonance imaging (rs-fMRI). In this pilot case-control study, we compare rs-fMRI data between age-matched depressed and non-depressed older adults. Methods: Older participants ( ge;55 years) with current major depressive disorder (MDD) were recruited to participate in an ongoing study of LLD, and were compared to the age-matched, non-depressed controls. Rs-fMRI data were collected using a 3-Tesla MRI system. In this study, a data-driven approach was chosen and an independent component analysis (ICA) was performed. Results: Seventeen subjects with MDD were compared to 31 controls. The depressed group showed increased connectivity in three main networks compared to the controls (p(corr) |
| 원문URL | http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=03553784&target=NART&cn=NART73369181 |
| 첨부파일 |
추가정보
| 과학기술표준분류 | |
|---|---|
| ICT 기술분류 | |
| DDC 분류 | |
| 주제어 (키워드) | Late-life,Geriatric depression,Functional connectivity,Neuroimaging,fMRI |