Vertebral compression fractures after spine irradiation using conventional fractionation in patients with metastatic colorectal cancer
기관명 | NDSL |
---|---|
저널명 | Radiation oncology journal : ROJ |
ISSN | 2234-1900,2234-3156 |
ISBN |
저자(한글) | Rhee, Woo Joong,Kim, Kyung Hwan,Chang, Jee Suk,Kim, Hyun Ju,Choi, Seohee,Koom, Woong Sub |
---|---|
저자(영문) | |
소속기관 | |
소속기관(영문) | |
출판인 | |
간행물 번호 | |
발행연도 | 2014-01-01 |
초록 | Purpose: To evaluate the risk of vertebral compression fracture (VCF) after conventional radiotherapy (RT) for colorectal cancer (CRC) with spine metastasis and to identify risk factors for VCF in metastatic and non-metastatic irradiated spines. Materials and Methods: We retrospectively reviewed 68 spinal segments in 16 patients who received conventional RT between 2009 and 2012. Fracture was defined as a newly developed VCF or progression of an existing fracture. The target volume included all metastatic spinal segments and one additional non-metastatic vertebra adjacent to the tumor-involved spines. Results: The median follow-up was 7.8 months. Among all 68 spinal segments, there were six fracture events (8.8%) including three new VCFs and three fracture progressions. Observed VCF rates in vertebral segments with prior irradiation or pre-existing compression fracture were 30.0% and 75.0% respectively, compared with 5.2% and 4.7% for segments without prior irradiation or pre-existing compression fracture, respectively (both p |
원문URL | http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=03553784&target=NART&cn=JAKO201406233839343 |
첨부파일 |
과학기술표준분류 | |
---|---|
ICT 기술분류 | |
DDC 분류 | |
주제어 (키워드) | Spinal neoplasm,Compression fractures,Spinal fractures,Radiotherapy,Colorectal cancer,Risk factors |