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논문 기본정보
치주염증에 대한 마치현 및 금전초 에탄올 추출물의 억제 효과
논문 개요
| 기관명 | NDSL |
|---|---|
| 저널명 | 동의생리병리학회지 = Journal of physiology pathology in Korean Medicine |
| ISSN | 1738-7698,2283-2529 |
| ISBN |
논문저자 및 소속기관 정보
| 저자(한글) | 박영미,이영래,박상훈,이봉근,박연주,오홍근,문대인,손민우,강양규,김옥진,이석련,이충훈,김민석,이학용 |
|---|---|
| 저자(영문) | |
| 소속기관 | |
| 소속기관(영문) | |
| 출판인 | |
| 간행물 번호 | |
| 발행연도 | 2015-01-01 |
| 초록 | Both Portulaca oleracea (PO) and Glechoma hederacea (GH) have been used as traditional medicine due to the multiple pharmacological activities. However, the effects of PO and GH in the pathology of periodontitis is still elusive. In this study, we examined anti-microbial activity of PO ethanol extract (POEE) and GH ethanol extract (GHEE) in vitro, and physiological effects of POEE and GHEE on the cell inflammatory responses and the severity of periodontitis were determined using the rat periodontitis model. Our results indicate that POEE and GHEE had no effects on the proliferation of streptococcus mutans and on LPS-mediated inflammatory responses in gingival fibroblast cells. Notably, ingestion of POEE and GHEE resulted in attenuating the severity of periodontitis and population change of immune cells. These data suggests that PO and GH should be considered as candidates for relieving the severity of periondontitis. |
| 원문URL | http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=03553784&target=NART&cn=JAKO201508449473777 |
| 첨부파일 |
추가정보
| 과학기술표준분류 | |
|---|---|
| ICT 기술분류 | |
| DDC 분류 | |
| 주제어 (키워드) | Portulaca oleracea,periodontitis,streptococcus mutans |